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Chemical structure of Lanabecestat

GC19217

Lanabecestat

Lanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0·4 nM

ChemicalCAS1383982-64-6MW412.53FormulaC26H28N4O
CAS number
1383982-64-6
Molecular weight
412.53
Formula
C26H28N4O
Solubility
DMSO : ≥ 100 mg/mL (242·41 mM)
InChIKey
WKDNQONLGXOZRG-BOPKNSRXSA-N
Catalogue number
GC19217
Brand
GLPBIO
Computed properties PubChem CID 67979346 · XLogP 3 · TPSA 72.9 Ų · H-bond donors 1
XLogP
3
TPSA
72.9 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
31

SMILES CC#CC1=CC(=CN=C1)C2=CC3=C(CC4([C@]35N=C(C(=N5)N)C)CCC(CC4)OC)C=C2

Computed descriptors from PubChem (CID 67979346), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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