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Chemical structure of Ibiglustat

GC19196

Ibiglustat

Also known as [(3S)-1-azabicyclo[2.2.2]octan-3-yl] N-[2-[2-(4-fluorophenyl)-1,3-thiazol-4-yl]propan-2-yl]carbamate

Ibiglustat is an inhibitor of glucosylceramide synthase extracted from patent WO 2015089067 A1, compound example 64

ChemicalCAS1401090-53-6MW389.49FormulaC20H24FN3O2S
CAS number
1401090-53-6
Molecular weight
389.49
Formula
C20H24FN3O2S
Solubility
DMSO : ≥ 75 mg/mL (192·56 mM)
InChIKey
YFHRCLAKZBDRHN-MRXNPFEDSA-N
Catalogue number
GC19196
Brand
GLPBIO
Computed properties PubChem CID 60199242 · XLogP 3.5 · TPSA 82.7 Ų · H-bond donors 1
XLogP
3.5
TPSA
82.7 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
27

SMILES CC(C)(C1=CSC(=N1)C2=CC=C(C=C2)F)NC(=O)O[C@@H]3CN4CCC3CC4

Computed descriptors from PubChem (CID 60199242), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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