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Chemical structure of HA15

GC19188

HA15

Also known as N-[4-[3-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]phenyl]-1,3-thiazol-2-yl]acetamide

HA15 is a molecule that specifically targets BiP/GRP78/HSPA5, binding to and inhibiting its ATPase activity, which leads to the dissociation of BiP from PERK, IRE1α, and ATF6, thereby triggering endoplasmic reticulum stress

ChemicalCAS1609402-14-3MW466.58FormulaC23H22N4O3S2
CAS number
1609402-14-3
Molecular weight
466.58
Formula
C23H22N4O3S2
Solubility
DMSO ： ≥ 50 mg/mL (107·16 mM);Water ： ＜ 0·1 mg/mL (insoluble)
InChIKey
LBSMEKVVMYSTIH-UHFFFAOYSA-N
Catalogue number
GC19188
Brand
GLPBIO
Computed properties PubChem CID 73890923 · XLogP 4 · TPSA 128 Ų · H-bond donors 2
XLogP
4
TPSA
128 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
32

SMILES CC(=O)NC1=NC(=CS1)C2=CC(=CC=C2)NS(=O)(=O)C3=CC=CC4=C3C=CC=C4N(C)C

Computed descriptors from PubChem (CID 73890923), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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