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Chemical structure of GSK2982772

GC19182

GSK2982772

Also known as 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

GSK2982772 is a potent and ATP competitive RIP1 inhibitor with an IC50 of 16 nM

ChemicalCAS1622848-92-3MW377.4FormulaC20H19N5O3
CAS number
1622848-92-3
Molecular weight
377.4
Formula
C20H19N5O3
Solubility
DMSO : ≥ 100 mg/mL (264·97 mM)
InChIKey
LYPAFUINURXJSG-AWEZNQCLSA-N
Catalogue number
GC19182
Brand
GLPBIO
Computed properties PubChem CID 77108121 · XLogP 2.4 · TPSA 100 Ų · H-bond donors 2
XLogP
2.4
TPSA
100 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
28

SMILES CN1C2=CC=CC=C2OC[C@@H](C1=O)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4

Computed descriptors from PubChem (CID 77108121), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.