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Chemical structure of Glucagon receptor antagonists-4

GC19170

Glucagon receptor antagonists-4

Also known as 3-[[4-[(1S)-1-[3,5-dimethyl-4-[4-(trifluoromethyl)pyrazol-1-yl]phenoxy]butyl]benzoyl]amino]propanoic acid

Glucagon receptor antagonists-4 is a highly potent, non-peptide and orally active glucagon receptor antagonist

ChemicalCAS1393124-08-7MW503.51FormulaC26H28F3N3O4
CAS number
1393124-08-7
Molecular weight
503.51
Formula
C26H28F3N3O4
Solubility
DMSO : ≥ 30 mg/mL (59·58 mM)
InChIKey
IBDYYOQKQCCSDP-QFIPXVFZSA-N
Catalogue number
GC19170
Brand
GLPBIO
Computed properties PubChem CID 60151939 · XLogP 5 · TPSA 93.5 Ų · H-bond donors 2
XLogP
5
TPSA
93.5 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
36

SMILES CCC[C@@H](C1=CC=C(C=C1)C(=O)NCCC(=O)O)OC2=CC(=C(C(=C2)C)N3C=C(C=N3)C(F)(F)F)C

Computed descriptors from PubChem (CID 60151939), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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