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Chemical structure of Glesatinib hydrochloride

GC19166

Glesatinib hydrochloride

Also known as N-[[3-fluoro-4-[2-[5-[(2-methoxyethylamino)methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxyphenyl]carbamothioyl]-2-(4-fluorophenyl)acetamide;hydrochloride

Glesatinib hydrochloride is an inhibitor of the MET and Axl receptor tyrosine kinase pathways, which drive tumour growth when altered

ChemicalCAS1123838-51-6MW656.17FormulaC31H28ClF2N5O3S2
CAS number
1123838-51-6
Molecular weight
656.17
Formula
C31H28ClF2N5O3S2
Solubility
DMSO : ≥ 28 mg/mL (42·67 mM)
InChIKey
TUVXGVPWXBWWEP-UHFFFAOYSA-N
Catalogue number
GC19166
Brand
GLPBIO
Computed properties PubChem CID 127255607 · TPSA 158 Ų · H-bond donors 4 · H-bond acceptors 10
TPSA
158 Ų
H-bond donors
4
H-bond acceptors
10
Rotatable bonds
11
Heavy atoms
44

SMILES COCCNCC1=CN=C(C=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=C(C=C5)F)F.Cl

Computed descriptors from PubChem (CID 127255607), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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