Loading...
Chemical structure of Fulacimstat

GC19159

Fulacimstat

Also known as 1-(3-methyl-2-oxo-1,3-benzoxazol-6-yl)-2,4-dioxo-3-[(1R)-4-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]pyrimidine-5-carboxylic acid

Fulacimstat is an orally available chymase inhibitor, with IC50s of 4, 3 nM for human and hamster chymase enzyme, respectively

ChemicalCAS1488354-15-9MW487.38FormulaC23H16F3N3O6
CAS number
1488354-15-9
Molecular weight
487.38
Formula
C23H16F3N3O6
Solubility
DMSO ： 5 mg/mL (10·26 mM)
InChIKey
JDARDSVOVYVQST-MRXNPFEDSA-N
Catalogue number
GC19159
Brand
GLPBIO
Computed properties PubChem CID 91758792 · XLogP 3.4 · TPSA 107 Ų · H-bond donors 1
XLogP
3.4
TPSA
107 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
3
Heavy atoms
35

SMILES CN1C2=C(C=C(C=C2)N3C=C(C(=O)N(C3=O)[C@@H]4CCC5=C4C=CC=C5C(F)(F)F)C(=O)O)OC1=O

Computed descriptors from PubChem (CID 91758792), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.