GC19145
ETP-46321
Also known as 5-[2-[(4-methylsulfonylpiperazin-1-yl)methyl]-8-morpholin-4-ylimidazo[1,2-a]pyrazin-6-yl]pyrimidin-2-amine
ETP-46321 is a potent and orally bioavailable PI3Kα and PI3Kδ inhibitor with Kiapps of 2·3 and 14·2 nM, respectively
ChemicalCAS1252594-99-2MW473.55FormulaC20H27N9O3S
- CAS number
- 1252594-99-2
- Molecular weight
- 473.55
- Formula
- C20H27N9O3S
- Solubility
- DMSO ： ≥ 33 mg/mL (69·69 mM)
- InChIKey
- OHKDVDMWRKFZRB-UHFFFAOYSA-N
- Catalogue number
- GC19145
- Brand
- GLPBIO
Computed properties PubChem CID 46927938 · XLogP -0.7 · TPSA 143 Ų · H-bond donors 1
- XLogP
- -0.7
- TPSA
- 143 Ų
- H-bond donors
- 1
- H-bond acceptors
- 11
- Rotatable bonds
- 5
- Heavy atoms
- 33
SMILES CS(=O)(=O)N1CCN(CC1)CC2=CN3C=C(N=C(C3=N2)N4CCOCC4)C5=CN=C(N=C5)N
Computed descriptors from PubChem (CID 46927938), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il