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Chemical structure of Tomivosertib

GC19131

Tomivosertib

Also known as 6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione

eFT508 is a potent, highly selective, and orally bioavailable MNK1 and MNK2 inhibitor, with IC50s of 1-2 nM against both isoforms

ChemicalCAS1849590-01-7MW340.38FormulaC17H20N6O2
CAS number
1849590-01-7
Molecular weight
340.38
Formula
C17H20N6O2
Solubility
DMSO : 4·35 mg/mL (12·78 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
HKTBYUWLRDZAJK-UHFFFAOYSA-N
Catalogue number
GC19131
Brand
GLPBIO
Computed properties PubChem CID 118598754 · XLogP 1.3 · TPSA 113 Ų · H-bond donors 3
XLogP
1.3
TPSA
113 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
25

SMILES CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3

Computed descriptors from PubChem (CID 118598754), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.