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Chemical structure of Doravirine

GC19126

Doravirine

Also known as 3-chloro-5-[[1-[(4-methyl-5-oxo-1H-1,2,4-triazol-3-yl)methyl]-2-oxo-4-(trifluoromethyl)-3-pyridinyl]oxy]benzonitrile

Doravirine is a novel non-nucleoside inhibitor of HIV-1 reverse transcriptase with potent activity against wild-type virus (95% inhibitory concentration 19 nM, 50% human serum)

ChemicalCAS1338225-97-0MW425.75FormulaC17H11ClF3N5O3
CAS number
1338225-97-0
Molecular weight
425.75
Formula
C17H11ClF3N5O3
Solubility
DMSO ： ≥ 30 mg/mL (70·46 mM)
InChIKey
ZIAOVIPSKUPPQW-UHFFFAOYSA-N
Catalogue number
GC19126
Brand
GLPBIO
Computed properties PubChem CID 58460047 · XLogP 2.1 · TPSA 98 Ų · H-bond donors 1
XLogP
2.1
TPSA
98 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
29

SMILES CN1C(=NNC1=O)CN2C=CC(=C(C2=O)OC3=CC(=CC(=C3)C#N)Cl)C(F)(F)F

Computed descriptors from PubChem (CID 58460047), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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