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Chemical structure of DBPR108

GC19120

DBPR108

Also known as (2S,4S)-4-fluoro-1-[2-[(2-methyl-4-oxo-4-pyrrolidin-1-ylbutan-2-yl)amino]acetyl]pyrrolidine-2-carbonitrile

DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9

ChemicalCAS1186426-66-3MW324.39FormulaC16H25FN4O2
CAS number
1186426-66-3
Molecular weight
324.39
Formula
C16H25FN4O2
Solubility
DMSO ： ≥ 25 mg/mL (77·07 mM)
InChIKey
VQKSCYBKUIDZEI-STQMWFEESA-N
Catalogue number
GC19120
Brand
GLPBIO
Computed properties PubChem CID 44201003 · XLogP 0.2 · TPSA 76.4 Ų · H-bond donors 1
XLogP
0.2
TPSA
76.4 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
23

SMILES CC(C)(CC(=O)N1CCCC1)NCC(=O)N2C[C@H](C[C@H]2C#N)F

Computed descriptors from PubChem (CID 44201003), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.