GC19048
AZD-0364
Also known as (6R)-7-[(3,4-difluorophenyl)methyl]-6-(methoxymethyl)-2-[5-methyl-2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5,6-dihydroimidazo[1,2-a]pyrazin-8-one
AZD-0364 (AZD0364) is a potent and selective ERK2 inhibitor extracted from patent WO2017080979A1, compound example 18, has an IC50 of 0·6 nM
ChemicalCAS2097416-76-5MW494.5FormulaC24H24F2N8O2
- CAS number
- 2097416-76-5
- Molecular weight
- 494.5
- Formula
- C24H24F2N8O2
- Solubility
- DMSO ： ≥ 100 mg/mL (202·22 mM)
- InChIKey
- HVIGNZUDBVLTLU-MRXNPFEDSA-N
- Catalogue number
- GC19048
- Brand
- GLPBIO
Computed properties PubChem CID 129116690 · XLogP 2 · TPSA 103 Ų · H-bond donors 1
- XLogP
- 2
- TPSA
- 103 Ų
- H-bond donors
- 1
- H-bond acceptors
- 9
- Rotatable bonds
- 7
- Heavy atoms
- 36
SMILES CC1=CN=C(N=C1C2=CN3C[C@@H](N(C(=O)C3=N2)CC4=CC(=C(C=C4)F)F)COC)NC5=CC=NN5C
Computed descriptors from PubChem (CID 129116690), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il