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Chemical structure of Dasabuvir

GC19015

Dasabuvir

Also known as N-[6-[3-tert-butyl-5-(2,4-dioxopyrimidin-1-yl)-2-methoxyphenyl]naphthalen-2-yl]methanesulfonamide

Dasabuvir is a nonnucleoside inhibitor of the RNA-dependent RNA polymerase encoded by the HCV NS5B gene, inhibits recombinant NS5B polymerases derived from HCV genotype 1a and 1b clinical isolates, with IC50 between 2·2 and 10·7 nM

ChemicalCAS1132935-63-7MW493.57FormulaC26H27N3O5S
CAS number
1132935-63-7
Molecular weight
493.57
Formula
C26H27N3O5S
Solubility
DMSO ： ≥ 46 mg/mL (93·20 mM)
InChIKey
NBRBXGKOEOGLOI-UHFFFAOYSA-N
Catalogue number
GC19015
Brand
GLPBIO
Computed properties PubChem CID 56640146 · XLogP 4.3 · TPSA 113 Ų · H-bond donors 2
XLogP
4.3
TPSA
113 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
35

SMILES CC(C)(C)C1=CC(=CC(=C1OC)C2=CC3=C(C=C2)C=C(C=C3)NS(=O)(=O)C)N4C=CC(=O)NC4=O

Computed descriptors from PubChem (CID 56640146), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.