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Chemical structure of 3-TYP

GC19013

3-TYP

Also known as 3-(2H-triazol-4-yl)pyridine

3-TYP inhibit SIRT3 with an IC50 of 16 nM, and is more potent over SIRT1 and SIRT2 with IC50 of 88 nM and 92 nM, respectively

ChemicalCAS120241-79-4MW146.15FormulaC7H6N4
CAS number
120241-79-4
Molecular weight
146.15
Formula
C7H6N4
Solubility
DMSO : 100 mg/mL (684·23 mM);Ethanol : 16·67 mg/mL (114·06 mM)
InChIKey
VYXFEFOIYPNBFK-UHFFFAOYSA-N
Catalogue number
GC19013
Brand
GLPBIO
Computed properties PubChem CID 9833992 · XLogP 0.2 · TPSA 54.5 Ų · H-bond donors 1
XLogP
0.2
TPSA
54.5 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
11

SMILES C1=CC(=CN=C1)C2=NNN=C2

Computed descriptors from PubChem (CID 9833992), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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