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Chemical structure of CAY10638

GC18893

CAY10638

Also known as (5Z)-5-[[4-(2-thiophen-2-ylethoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione

Prostaglandins have a short life in vivo because NAD+-dependent 15-hydroxy prostaglandin dehydrogenase (15-PGDH) catalyzes their oxidation to 15-keto metabolites with greatly reduced biological activity

ChemicalCAS1221413-57-5MW331.4FormulaC16H13NO3S2
CAS number
1221413-57-5
Molecular weight
331.4
Formula
C16H13NO3S2
Solubility
DMF: 30 mg/ml,DMF:PBS (pH 7·2) (1:9): 0·1 mg/ml,DMSO: 25 mg/ml
InChIKey
NTKWOUHXDKSPIX-UVTDQMKNSA-N
Catalogue number
GC18893
Brand
GLPBIO
Computed properties PubChem CID 46233465 · XLogP 3.8 · TPSA 109 Ų · H-bond donors 1
XLogP
3.8
TPSA
109 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
22

SMILES C1=CSC(=C1)CCOC2=CC=C(C=C2)/C=C\3/C(=O)NC(=O)S3

Computed descriptors from PubChem (CID 46233465), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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