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Chemical structure of 16,16-dimethyl Prostaglandin F2α

GC18774

16,16-dimethyl Prostaglandin F2α

Also known as (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]cyclopentyl]hept-5-enoic acid

16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α

ChemicalCAS39746-23-1MW382.5FormulaC22H38O5
CAS number
39746-23-1
Molecular weight
382.5
Formula
C22H38O5
Solubility
10 mM Na2CO3: >6·5 mg/ml (from PGF2a),DMF: >100 mg/ml (from PGF2a),DMSO: >100 mg/ml (from PGF2a),Ethanol: >100 mg/ml (from PGF2a),PBS pH 7·2: >10 mg/ml (from PGF2a)
InChIKey
YMRWVEHSLXJOCD-SCOYTADVSA-N
Catalogue number
GC18774
Brand
GLPBIO
Computed properties PubChem CID 6441607 · XLogP 3.6 · TPSA 98 Ų · H-bond donors 4
XLogP
3.6
TPSA
98 Ų
H-bond donors
4
H-bond acceptors
5
Rotatable bonds
12
Heavy atoms
27

SMILES CCCCC(C)(C)[C@@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)O)O)O

Computed descriptors from PubChem (CID 6441607), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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