Loading...
Chemical structure of MZ1

GC18729

MZ1

Also known as (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4)

ChemicalCAS1797406-69-9MW1002.6FormulaC49H60ClN9O8S2
CAS number
1797406-69-9
Molecular weight
1002.6
Formula
C49H60ClN9O8S2
Solubility
DMF： 30 mg/mL,DMSO： 30 mg/mL,Ethanol： 30 mg/mL,Ethanol：PBS (pH7·2) (1：7)： 0·12 mg/mL
InChIKey
PTAMRJLIOCHJMQ-PYNGZGNASA-N
Catalogue number
GC18729
Brand
GLPBIO
Computed properties PubChem CID 122201421 · XLogP 5 · TPSA 268 Ų · H-bond donors 4
XLogP
5
TPSA
268 Ų
H-bond donors
4
H-bond acceptors
14
Rotatable bonds
21
Heavy atoms
69

SMILES CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N4C[C@@H](C[C@H]4C(=O)NCC5=CC=C(C=C5)C6=C(N=CS6)C)O)C(C)(C)C)C7=CC=C(C=C7)Cl)C

Computed descriptors from PubChem (CID 122201421), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.