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Chemical structure of Bisindolylmaleimide I, Hydrochloride

GC18725

Bisindolylmaleimide I, Hydrochloride

Also listed as Bisindolylmaleimide I (hydrochloride)

Bisindolylmaleimide I (BIM I) is a highly selective, cell-permeable, and reversible PKC inhibitor (Ki = 14 nM) that is structurally similar to the poorly selective PKC inhibitor staurosporine

ChemicalCAS176504-36-2MW449FormulaC25H24N4O2·HCl
CAS number
176504-36-2
Molecular weight
449
Formula
C25H24N4O2·HCl
Solubility
DMF： 10 mg/mL,DMSO： 16 mg/mL,DMSO：PBS(pH 7·2) (1：4)： 0·2 mg/mL
InChIKey
XRAMWNCMYJHGGH-UHFFFAOYSA-N
Catalogue number
GC18725
Brand
GLPBIO
Computed properties PubChem CID 6419775 · TPSA 70.1 Ų · H-bond donors 3 · H-bond acceptors 3
TPSA
70.1 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
32

SMILES CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54.Cl

Computed descriptors from PubChem (CID 6419775), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.