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Chemical structure of Ro 31-8830 (hydrochloride)

GC18716

Ro 31-8830 (hydrochloride)

Also listed as Bisindolylmaleimide XI (hydrochloride)

Bisindolylmaleimide XI (BIM XI) is a selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC50 = 9 nM) and 4-fold greater selectivity for PKCβI (IC50 = 28 nM) over Ca2+-independent PKCε (IC50 = 108 nM)

ChemicalCAS145333-02-4MW489FormulaC28H28N4O2·HCl
CAS number
145333-02-4
Molecular weight
489
Formula
C28H28N4O2·HCl
Solubility
DMSO ： 5 mg/mL (10·22 mM; Need ultrasonic and warming)
InChIKey
WMVQGKBSNAIMHI-UHFFFAOYSA-N
Catalogue number
GC18716
Brand
GLPBIO
Computed properties PubChem CID 5311362 · TPSA 59.3 Ų · H-bond donors 2 · H-bond acceptors 3
TPSA
59.3 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
35

SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CC5=C(C=C4)C=C6N5CCC(C6)CN(C)C.Cl

Computed descriptors from PubChem (CID 5311362), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.