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Chemical structure of BAY-299

GC18508

BAY-299

Also known as 6-(3-hydroxypropyl)-2-(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione

BAY-299 is a potent and selective inhibitor of the bromodomain and PHD finger-containing (BRPF) family protein BRD1 (IC50 = 6 nM), also known as BRPF2, and the second bromodomain of transcription initiation factor TFIID subunits 1 (TAF1; IC50 = 13 nM)

ChemicalCAS2080306-23-4MW429.5FormulaC25H23N3O4
CAS number
2080306-23-4
Molecular weight
429.5
Formula
C25H23N3O4
Solubility
DMF: 30 mg/ml,DMSO: 20 mg/ml
InChIKey
OFWWWKWUCDUISA-UHFFFAOYSA-N
Catalogue number
GC18508
Brand
GLPBIO
Computed properties PubChem CID 122705990 · XLogP 3 · TPSA 81.2 Ų · H-bond donors 1
XLogP
3
TPSA
81.2 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
32

SMILES CC1=CC2=C(C=C1N3C(=O)C4=C5C(=C(C=C4)CCCO)C=CC=C5C3=O)N(C(=O)N2C)C

Computed descriptors from PubChem (CID 122705990), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Pricing
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Documents
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