GC18491
CFI-402257
Also known as N-cyclopropyl-4-[7-[(3-hydroxy-3-methylcyclobutyl)methylamino]-5-pyridin-3-yloxypyrazolo[1,5-a]pyrimidin-3-yl]-2-methylbenzamide
CFI-402257 is a selective inhibitor of Mps1, CFI-402257 inhibited Mps1 with an IC50 value of 1·2 ± 0·4 nM, and was ATP competitive with a Ki value of 0·09 ± 0·02 nM, It has high specificity, selectivity and potency
ChemicalCAS1610759-22-2MW498.6FormulaC28H30N6O3
- CAS number
- 1610759-22-2
- Molecular weight
- 498.6
- Formula
- C28H30N6O3
- Solubility
- DMSO ： ≥ 125 mg/mL (233·63 mM)
- InChIKey
- PMQUGSPFUBGJCZ-UHFFFAOYSA-N
- Catalogue number
- GC18491
- Brand
- GLPBIO
Computed properties PubChem CID 118086034 · XLogP 3.6 · TPSA 114 Ų · H-bond donors 3
- XLogP
- 3.6
- TPSA
- 114 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 37
SMILES CC1=C(C=CC(=C1)C2=C3N=C(C=C(N3N=C2)NCC4CC(C4)(C)O)OC5=CN=CC=C5)C(=O)NC6CC6
Computed descriptors from PubChem (CID 118086034), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il