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Chemical structure of DG-051

GC18471

DG-051

Also known as 4-[(2S)-2-[[4-(4-chlorophenoxy)phenoxy]methyl]pyrrolidin-1-yl]butanoic acid;hydrochloride

DG-051 is a potent, orally bioavailable leukotriene A4 hydrolase (LTA4H) inhibitor (Kd = 25 nM; IC50 = 47 nM), the enzyme that catalyzes the rate-determining step in the synthesis of LTB4

ChemicalCAS929915-58-2MW426.3FormulaC21H24ClNO4·HCl
CAS number
929915-58-2
Molecular weight
426.3
Formula
C21H24ClNO4·HCl
Solubility
DMF： 20 mg/ml,DMSO： 12·5 mg/ml,Ethanol： 12·5 mg/ml,PBS (pH 7·2)： 2 mg/ml
InChIKey
UCPVOTSNNAVKNE-LMOVPXPDSA-N
Catalogue number
GC18471
Brand
GLPBIO
Computed properties PubChem CID 44818987 · TPSA 59 Ų · H-bond donors 2 · H-bond acceptors 5
TPSA
59 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
9
Heavy atoms
28

SMILES C1C[C@H](N(C1)CCCC(=O)O)COC2=CC=C(C=C2)OC3=CC=C(C=C3)Cl.Cl

Computed descriptors from PubChem (CID 44818987), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.