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Chemical structure of R-(-)-α-Methylhistamine (hydrochloride)

GC18397

R-(-)-α-Methylhistamine (hydrochloride)

Also known as (2R)-1-(1H-imidazol-5-yl)propan-2-amine;dihydrochloride

R-(-)-α-Methylhistamine (hydrochloride) is a potent, selective and brain-penetrant agonist of H3 histamine receptor, with a Kd of 50·3 nM

ChemicalCAS75614-89-0MW198.1FormulaC6H11N3·2HCl
CAS number
75614-89-0
Molecular weight
198.1
Formula
C6H11N3·2HCl
Solubility
DMF： inbsoluble,DMSO： 20 mg/ml,Ethanol： 1 mg/ml,PBS (pH 7·2)： 10 mg/ml
InChIKey
IZHCNQFUWDFPCW-ZJIMSODOSA-N
Catalogue number
GC18397
Brand
GLPBIO
Computed properties PubChem CID 11957567 · TPSA 54.7 Ų · H-bond donors 4 · H-bond acceptors 2
TPSA
54.7 Ų
H-bond donors
4
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
11

SMILES C[C@H](CC1=CN=CN1)N.Cl.Cl

Computed descriptors from PubChem (CID 11957567), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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