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Chemical structure of DSP

GC18378

DSP

Also known as (2,5-dioxopyrrolidin-1-yl) 3-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropyl]disulfanyl]propanoate

DSP is a cleavable ADC linker, used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS57757-57-0MW404.41FormulaC14H16N2O8S2
CAS number
57757-57-0
Molecular weight
404.41
Formula
C14H16N2O8S2
Solubility
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7·2) (1:4): 0·20 mg/ml
InChIKey
FXYPGCIGRDZWNR-UHFFFAOYSA-N
Catalogue number
GC18378
Brand
GLPBIO
Computed properties PubChem CID 93313 · XLogP -1.2 · TPSA 178 Ų · H-bond donors 0
XLogP
-1.2
TPSA
178 Ų
H-bond donors
0
H-bond acceptors
10
Rotatable bonds
11
Heavy atoms
26

SMILES C1CC(=O)N(C1=O)OC(=O)CCSSCCC(=O)ON2C(=O)CCC2=O

Computed descriptors from PubChem (CID 93313), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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