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Chemical structure of Calpain Inhibitor VI

GC18315

Calpain Inhibitor VI

Also known as (2S)-2-[(4-fluorophenyl)sulfonylamino]-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]butanamide

Calpain inhibitor VI is an inhibitor of the calcium-dependent cysteine proteases u-calpain (calpain-1; IC50 = 7·5 nM) and m-calpain (calpain-2; IC50 = 78 nM)

ChemicalCAS190274-53-4MW372.5FormulaC17H25FN2O4S
CAS number
190274-53-4
Molecular weight
372.5
Formula
C17H25FN2O4S
Solubility
DMSO： 5 mg/ml
InChIKey
WSJWUIDLGZAXID-HOCLYGCPSA-N
Catalogue number
GC18315
Brand
GLPBIO
Computed properties PubChem CID 9885817 · XLogP 3 · TPSA 101 Ų · H-bond donors 2
XLogP
3
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
25

SMILES CC(C)C[C@@H](C=O)NC(=O)[C@H](C(C)C)NS(=O)(=O)C1=CC=C(C=C1)F

Computed descriptors from PubChem (CID 9885817), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.