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Chemical structure of Fadrozole (hydrochloride)

GC18301

Fadrozole (hydrochloride)

Also known as 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile;hydrochloride

Fadrozole is a non-steroidal aromatase inhibitor (IC50s = 5 and 1·4 nM for human placental and rat ovarian microsomal aromatase, respectively)

ChemicalCAS102676-31-3MW259.7FormulaC14H13N3·HCl
CAS number
102676-31-3
Molecular weight
259.7
Formula
C14H13N3·HCl
Solubility
DMF: 5 mg/ml,DMSO: 10 mg/ml,DMSO:PBS(pH 7·2) (1:2): 0·3 mg/ml,Ethanol: 2 mg/ml
InChIKey
UKCVAQGKEOJTSR-UHFFFAOYSA-N
Catalogue number
GC18301
Brand
GLPBIO
Computed properties PubChem CID 59694 · TPSA 41.6 Ų · H-bond donors 1 · H-bond acceptors 2
TPSA
41.6 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
18

SMILES C1CC(N2C=NC=C2C1)C3=CC=C(C=C3)C#N.Cl

Computed descriptors from PubChem (CID 59694), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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