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Chemical structure of FTase Inhibitor I

GC18260

FTase Inhibitor I

Also known as (2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-sulfanylpropyl]amino]-3-methylbutyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid

FTase inhibitor I is a potent inhibitor of farnesyltransferase (FTase; IC50 = 21 nM) that is greater than 30-fold selective for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM)

ChemicalCAS149759-96-6MW470.7FormulaC22H38N4O3S2
CAS number
149759-96-6
Molecular weight
470.7
Formula
C22H38N4O3S2
Solubility
Water： Soluble
InChIKey
QISLMXIYRQCLIR-FUMNGEBKSA-N
Catalogue number
GC18260
Brand
GLPBIO
Computed properties PubChem CID 132887 · XLogP -0.1 · TPSA 143 Ų · H-bond donors 6
XLogP
-0.1
TPSA
143 Ų
H-bond donors
6
H-bond acceptors
8
Rotatable bonds
16
Heavy atoms
31

SMILES CC(C)[C@@H](CN[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)O)NC[C@H](CS)N

Computed descriptors from PubChem (CID 132887), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.