Loading...
Chemical structure of R-59-949

GC18246

R-59-949

Also known as 3-[2-[4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one

R-59-949 is an inhibitor of diacylglycerol kinase α (DGK-α) with an IC50 value of 300 nM in isolated platelet plasma membranes using exogenous diacylglycerol as a substrate

ChemicalCAS120166-69-0MW489.6FormulaC28H25F2N3OS
CAS number
120166-69-0
Molecular weight
489.6
Formula
C28H25F2N3OS
Solubility
DMF： 33 mg/ml,DMSO： 33 mg/ml,Ethanol： 1 mg/ml
InChIKey
ZCNBZFRECRPCKU-UHFFFAOYSA-N
Catalogue number
GC18246
Brand
GLPBIO
Computed properties PubChem CID 657356 · XLogP 5.6 · TPSA 67.7 Ų · H-bond donors 1
XLogP
5.6
TPSA
67.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
35

SMILES C1CN(CCC1=C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)CCN4C(=O)C5=CC=CC=C5NC4=S

Computed descriptors from PubChem (CID 657356), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.