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Chemical structure of Farampator

GC18223

Farampator

Also known as 2,1,3-benzoxadiazol-5-yl(piperidin-1-yl)methanone

Farampator is a positive allosteric modulator of AMPA receptors that has an EC50 value greater than 32 uM for evoking glutamate currents in isolated pyramidal neurons

ChemicalCAS211735-76-1MW231.3FormulaC12H13N3O2
CAS number
211735-76-1
Molecular weight
231.3
Formula
C12H13N3O2
Solubility
DMF: 30 mg/ml,DMF:PBS (pH7·2) (1:40): 25μ g/ml,DMSO: 20 mg/ml
InChIKey
XFVRBYKKGGDPAJ-UHFFFAOYSA-N
Catalogue number
GC18223
Brand
GLPBIO
Computed properties PubChem CID 4118151 · XLogP 1.5 · TPSA 59.2 Ų · H-bond donors 0
XLogP
1.5
TPSA
59.2 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
1
Heavy atoms
17

SMILES C1CCN(CC1)C(=O)C2=CC3=NON=C3C=C2

Computed descriptors from PubChem (CID 4118151), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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