Loading...
Chemical structure of OTX-015

GC17973

OTX-015

Also known as 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]-N-(4-hydroxyphenyl)acetamide

OTX-015 inhibits the binding of BRD2, BRD3, and BRD4 to acetylated histone 4 in a concentration-dependent manner, with IC50 values from 92-112nM

ChemicalCAS202590-98-5MW491.99FormulaC25H22ClN5O2S
CAS number
202590-98-5
Molecular weight
491.99
Formula
C25H22ClN5O2S
Solubility
≥ 24·6 mg/mL in DMSO, ≥ 106 mg/mL in EtOH with gentle warming
InChIKey
GNMUEVRJHCWKTO-FQEVSTJZSA-N
Catalogue number
GC17973
Brand
GLPBIO
Computed properties PubChem CID 9936746 · XLogP 4.5 · TPSA 121 Ų · H-bond donors 2
XLogP
4.5
TPSA
121 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
34

SMILES CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NC4=CC=C(C=C4)O)C5=CC=C(C=C5)Cl)C

Computed descriptors from PubChem (CID 9936746), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.