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Chemical structure of Palbociclib hydrochloride

GC17935

Palbociclib hydrochloride

Also listed as PD 0332991 (Palbociclib) HCl

PD 0332991, as an orally active potent and highly selective inhibitor of CDK4 and CDK6 kinases, can block pRb phosphorylation and subsequently inducing G1 arrest in sensitive cell lines in low nanomolar concentrations

ChemicalCAS827022-32-2MW483.99FormulaC24H30ClN7O2
CAS number
827022-32-2
Molecular weight
483.99
Formula
C24H30ClN7O2
Solubility
≥ 2·4mg/mL in DMSO, ≥ 24·2mg/mL in Water, ≥ 2·79 mg/mL in EtOH with ultrasonic and warming
InChIKey
STEQOHNDWONVIF-UHFFFAOYSA-N
Catalogue number
GC17935
Brand
GLPBIO
Computed properties PubChem CID 11431660 · TPSA 103 Ų · H-bond donors 3 · H-bond acceptors 8
TPSA
103 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
34

SMILES CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C.Cl

Computed descriptors from PubChem (CID 11431660), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.