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Chemical structure of Poziotinib

GC17916

Poziotinib

Also known as 1-[4-[4-(3,4-dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one

A irreversible pan-HER inhibitor

ChemicalCAS1092364-38-9MW491.34FormulaC23H21Cl2FN4O3
CAS number
1092364-38-9
Molecular weight
491.34
Formula
C23H21Cl2FN4O3
Solubility
≥ 94·2mg/mL in DMSO
InChIKey
LPFWVDIFUFFKJU-UHFFFAOYSA-N
Catalogue number
GC17916
Brand
GLPBIO
Computed properties PubChem CID 25127713 · XLogP 5.4 · TPSA 76.6 Ų · H-bond donors 1
XLogP
5.4
TPSA
76.6 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
6
Heavy atoms
33

SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=C(C(=C(C=C3)Cl)Cl)F)OC4CCN(CC4)C(=O)C=C

Computed descriptors from PubChem (CID 25127713), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.