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Chemical structure of JP1302

GC17884

JP1302

Also known as N-[4-(4-methylpiperazin-1-yl)phenyl]acridin-9-amine

JP1302 is a potent, selective, high affinity antagonist of the α2C-adrenoceptor, with a Kb of 16 nM and a Ki of 28 nM for the human α2C-receptor

ChemicalCAS80259-18-3MW368.47FormulaC24H24N4
CAS number
80259-18-3
Molecular weight
368.47
Formula
C24H24N4
InChIKey
QZKGUNQLVFEEBA-UHFFFAOYSA-N
Catalogue number
GC17884
Brand
GLPBIO
Computed properties PubChem CID 540335 · XLogP 5 · TPSA 31.4 Ų · H-bond donors 1
XLogP
5
TPSA
31.4 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
28

SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=C4C=CC=CC4=NC5=CC=CC=C53

Computed descriptors from PubChem (CID 540335), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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