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Chemical structure of Copanlisib

GC17766

Copanlisib

Also listed as BAY 80-6946 (Copanlisib)

BAY 80-6946 (Copanlisib) (BAY 80-6946) is a potent, selective and ATP-competitive pan-class I PI3K inhibitor, with IC50s of 0·5 nM, 0·7 nM, 3·7 nM and 6·4 nM for PI3Kα, PI3Kδ, PI3Kβ and PI3Kγ, respectively· BAY 80-6946 (Copanlisib) has more than 2,000-fold selectivity against other lipid and protein kinases, except for mTOR· BAY 80-6946 (Copanlisib) has superior antitumor activity

ChemicalCAS1032568-63-0MW480.52FormulaC23H28N8O4
CAS number
1032568-63-0
Molecular weight
480.52
Formula
C23H28N8O4
Solubility
＜0·96mg/mL in DMSO, ＜1·022mg/mL in Water
InChIKey
MWYDSXOGIBMAET-UHFFFAOYSA-N
Catalogue number
GC17766
Brand
GLPBIO
Computed properties PubChem CID 135565596 · XLogP 0.3 · TPSA 140 Ų · H-bond donors 2
XLogP
0.3
TPSA
140 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
35

SMILES COC1=C(C=CC2=C3NCCN3C(=NC(=O)C4=CN=C(N=C4)N)N=C21)OCCCN5CCOCC5

Computed descriptors from PubChem (CID 135565596), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.