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Chemical structure of Sorafenib

GC17369

Sorafenib

Also known as 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide

Sorafenib acts as a multi-kinase inhibitor, targeting Raf-1 and B-Raf with IC50 values of 6 nM and 22 nM, respectively

ChemicalCAS284461-73-0MW464.82FormulaC21H16ClF3N4O3
CAS number
284461-73-0
Molecular weight
464.82
Formula
C21H16ClF3N4O3
Solubility
≥ 23·25mg/mL in DMSO
InChIKey
MLDQJTXFUGDVEO-UHFFFAOYSA-N
Catalogue number
GC17369
Brand
GLPBIO
Computed properties PubChem CID 216239 · XLogP 4.1 · TPSA 92.4 Ų · H-bond donors 3
XLogP
4.1
TPSA
92.4 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
32

SMILES CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F

Computed descriptors from PubChem (CID 216239), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.