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Chemical structure of Gliotoxin

GC17255

Gliotoxin

Also known as 7-hydroxy-11-(hydroxymethyl)-15-methyl-12,13-dithia-9,15-diazatetracyclo[9.2.2.01,9.03,8]pentadeca-3,5-diene-10,14-dione

Gliotoxin, an immunosuppressive mycotoxin produced by pathogenic strains of Aspergillus and other fungi, is a specific inhibitor of 20S proteasomal chymotrypsin activity with an IC50 of 10μM

ChemicalCAS67-99-2MW326.38FormulaC13H14N2O4S2
CAS number
67-99-2
Molecular weight
326.38
Formula
C13H14N2O4S2
Solubility
5mg/mL in DMSO, or in DMF
InChIKey
FIVPIPIDMRVLAY-UHFFFAOYSA-N
Catalogue number
GC17255
Brand
GLPBIO
Computed properties PubChem CID 3477 · XLogP -0.7 · TPSA 132 Ų · H-bond donors 2
XLogP
-0.7
TPSA
132 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
1
Heavy atoms
21

SMILES CN1C(=O)C23CC4=CC=CC(C4N2C(=O)C1(SS3)CO)O

Computed descriptors from PubChem (CID 3477), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.