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Chemical structure of MMP-13 Inhibitor

GC17245

MMP-13 Inhibitor

Also known as 4-N,6-N-bis[(4-fluoro-3-methylphenyl)methyl]pyrimidine-4,6-dicarboxamide

MMP-13 Inhibitor (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM

ChemicalCAS544678-85-5MW410.4FormulaC22H20F2N4O2
CAS number
544678-85-5
Molecular weight
410.4
Formula
C22H20F2N4O2
Solubility
≤0·5mg/ml in ethanol;2mg/ml in DMSO;2mg/ml in dimethyl formamide
InChIKey
PYFRREJCFXFNRR-UHFFFAOYSA-N
Catalogue number
GC17245
Brand
GLPBIO
Computed properties PubChem CID 5289110 · XLogP 3.3 · TPSA 84 Ų · H-bond donors 2
XLogP
3.3
TPSA
84 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
30

SMILES CC1=C(C=CC(=C1)CNC(=O)C2=CC(=NC=N2)C(=O)NCC3=CC(=C(C=C3)F)C)F

Computed descriptors from PubChem (CID 5289110), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.