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Chemical structure of Zibotentan

GC16862

Zibotentan

Also listed as Zibotentan (ZD4054)

Zibotentan (ZD4054) (ZD4054) is a potent, selective and orally active endothelin A (ETA) receptor antagonist with a Ki of 13 nM

ChemicalCAS186497-07-4MW424.43FormulaC19H16N6O4S
CAS number
186497-07-4
Molecular weight
424.43
Formula
C19H16N6O4S
Solubility
≥ 7·2mg/mL in DMSO
InChIKey
FJHHZXWJVIEFGJ-UHFFFAOYSA-N
Catalogue number
GC16862
Brand
GLPBIO
Computed properties PubChem CID 9910224 · XLogP 1.4 · TPSA 141 Ų · H-bond donors 1
XLogP
1.4
TPSA
141 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
6
Heavy atoms
30

SMILES CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4

Computed descriptors from PubChem (CID 9910224), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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