Loading...
Chemical structure of ARN-509

GC16840

ARN-509

Also known as 4-[7-[6-cyano-5-(trifluoromethyl)-3-pyridinyl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide

ARN-509 is a synthetic biaryl thiohydantoin compound that inhibits androgen receptor (AR), with an IC50 value of 16nM

ChemicalCAS956104-40-8MW477.43FormulaC21H15F4N5O2S
CAS number
956104-40-8
Molecular weight
477.43
Formula
C21H15F4N5O2S
Solubility
≥ 23·85mg/mL in DMSO
InChIKey
HJBWBFZLDZWPHF-UHFFFAOYSA-N
Catalogue number
GC16840
Brand
GLPBIO
Computed properties PubChem CID 24872560 · XLogP 3 · TPSA 121 Ų · H-bond donors 1
XLogP
3
TPSA
121 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
3
Heavy atoms
33

SMILES CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F

Computed descriptors from PubChem (CID 24872560), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.