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Chemical structure of Defactinib

GC16813

Defactinib

Also known as N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide

FAK phosphorylation inhibitor

ChemicalCAS1073154-85-4MW510.49FormulaC20H21F3N8O3S
CAS number
1073154-85-4
Molecular weight
510.49
Formula
C20H21F3N8O3S
Solubility
≥ 160·2mg/mL in DMSO
InChIKey
FWLMVFUGMHIOAA-UHFFFAOYSA-N
Catalogue number
GC16813
Brand
GLPBIO
Computed properties PubChem CID 25117126 · XLogP 1.4 · TPSA 150 Ų · H-bond donors 3
XLogP
1.4
TPSA
150 Ų
H-bond donors
3
H-bond acceptors
13
Rotatable bonds
8
Heavy atoms
35

SMILES CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F

Computed descriptors from PubChem (CID 25117126), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.