GC16619
CTEP (RO4956371)
Also known as 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine
CTEP (RO4956371) (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist ofmGlu5receptor withIC50of 2·2 nM, and shows > 1000-fold selectivity over other mGlu receptors
ChemicalCAS871362-31-1MW391.77FormulaC19H13ClF3N3O
- CAS number
- 871362-31-1
- Molecular weight
- 391.77
- Formula
- C19H13ClF3N3O
- Solubility
- ≥ 19·6mg/mL in DMSO
- InChIKey
- GOHCTCOGYKAJLZ-UHFFFAOYSA-N
- Catalogue number
- GC16619
- Brand
- GLPBIO
Computed properties PubChem CID 11646823 · XLogP 5.6 · TPSA 39.9 Ų · H-bond donors 0
- XLogP
- 5.6
- TPSA
- 39.9 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Rotatable bonds
- 4
- Heavy atoms
- 27
SMILES CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl
Computed descriptors from PubChem (CID 11646823), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il