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Chemical structure of Naloxonazine dihydrochloride

GC16588

Naloxonazine dihydrochloride

Also known as (4R,4aS,7E,7aS,12bS)-7-[(Z)-[(4R,4aS,7aS,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ylidene]hydrazinylidene]-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol;dihydrochloride

Naloxonazine dihydrochloride is a specific μ-opioid receptor antagonist with an IC50 of 5·4 nM

ChemicalCAS880759-65-9MW723.69FormulaC38H42N4O6·2HCl
CAS number
880759-65-9
Molecular weight
723.69
Formula
C38H42N4O6·2HCl
Solubility
Soluble to 25 mM in Water
InChIKey
VIAIHLLKDJKEKM-KZFJLXDDSA-N
Catalogue number
GC16588
Brand
GLPBIO
Computed properties PubChem CID 124080991 · TPSA 131 Ų · H-bond donors 6 · H-bond acceptors 10
TPSA
131 Ų
H-bond donors
6
H-bond acceptors
10
Rotatable bonds
5
Heavy atoms
50

SMILES C=CCN1CC[C@]23[C@H]4/C(=N/N=C\5/CC[C@]6([C@H]7CC8=C9[C@]6([C@@H]5OC9=C(C=C8)O)CCN7CC=C)O)/CC[C@]2([C@H]1CC1=C3C(=C(C=C1)O)O4)O.Cl.Cl

Computed descriptors from PubChem (CID 124080991), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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