GC16480
AM 281
Also known as 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide
AM 281 is a high-affinity and selective CB2 receptor antagonist with an IC50 of 13μM· AM 281 is used to study the role of the endocannabinoid system in various physiological and pathological processes and has potential applications in the research of inflammation, pain, and neurodegenerative diseases
ChemicalCAS202463-68-1MW557.22FormulaC21H19Cl2IN4O2
- CAS number
- 202463-68-1
- Molecular weight
- 557.22
- Formula
- C21H19Cl2IN4O2
- Solubility
- ≥ 1·86mg/mL in DMSO with ultrasonic and warming
- InChIKey
- AJFFBPZYXRNAIC-UHFFFAOYSA-N
- Catalogue number
- GC16480
- Brand
- GLPBIO
Computed properties PubChem CID 4302962 · XLogP 5.3 · TPSA 59.4 Ų · H-bond donors 1
- XLogP
- 5.3
- TPSA
- 59.4 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Rotatable bonds
- 4
- Heavy atoms
- 30
SMILES CC1=C(N(N=C1C(=O)NN2CCOCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I
Computed descriptors from PubChem (CID 4302962), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il