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Chemical structure of Cediranib

GC16421

Cediranib

Also listed as Cediranib (AZD217)

Cediranib (AZD217) (AZD2171) is a highly potent, orally available VEGFR tyrosine kinase inhibitor with IC50s of <1, <3, 5, 5, 36, 2 nM for Flt1, KDR, Flt4, PDGFRα, PDGFRβ, c-Kit, respectively

ChemicalCAS288383-20-0MW450.51FormulaC25H27FN4O3
CAS number
288383-20-0
Molecular weight
450.51
Formula
C25H27FN4O3
Solubility
≥ 22·5mg/mL in DMSO
InChIKey
XXJWYDDUDKYVKI-UHFFFAOYSA-N
Catalogue number
GC16421
Brand
GLPBIO
Computed properties PubChem CID 9933475 · XLogP 4.9 · TPSA 72.5 Ų · H-bond donors 1
XLogP
4.9
TPSA
72.5 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
33

SMILES CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5

Computed descriptors from PubChem (CID 9933475), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.