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Chemical structure of CA 074

GC16317

CA 074

Also known as (2S)-1-[(2S,3S)-3-methyl-2-[[(3S)-3-(propylcarbamoyl)oxirane-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carboxylic acid

CA 074 is a selective inhibitor of cathepsin B with a Ki value of 2-5 nM· CA 074 is 10000-30000 times more potent against purified rat cathepsin B than against cathepsin H and L

ChemicalCAS134448-10-5MW383.44FormulaC18H29N3O6
CAS number
134448-10-5
Molecular weight
383.44
Formula
C18H29N3O6
Solubility
≥ 19·17mg/mL in DMSO
InChIKey
ZEZGJKSEBRELAS-KSFNBINOSA-N
Catalogue number
GC16317
Brand
GLPBIO
Computed properties PubChem CID 122165 · XLogP 0.9 · TPSA 128 Ų · H-bond donors 3
XLogP
0.9
TPSA
128 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
9
Heavy atoms
27

SMILES CCCNC(=O)[C@@H]1C(O1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N2CCC[C@H]2C(=O)O

Computed descriptors from PubChem (CID 122165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.