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Chemical structure of MYK-461

GC15858

MYK-461

Also known as 6-[[(1S)-1-phenylethyl]amino]-3-propan-2-yl-1H-pyrimidine-2,4-dione

MYK-461 (MYK461) is an orally active modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively

ChemicalCAS1642288-47-8MW273.33FormulaC15H19N3O2
CAS number
1642288-47-8
Molecular weight
273.33
Formula
C15H19N3O2
Solubility
≥ 13·65mg/mL in DMSO
InChIKey
RLCLASQCAPXVLM-NSHDSACASA-N
Catalogue number
GC15858
Brand
GLPBIO
Computed properties PubChem CID 117761397 · XLogP 2.1 · TPSA 61.4 Ų · H-bond donors 2
XLogP
2.1
TPSA
61.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
20

SMILES C[C@@H](C1=CC=CC=C1)NC2=CC(=O)N(C(=O)N2)C(C)C

Computed descriptors from PubChem (CID 117761397), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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