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Chemical structure of Pamapimod

GC15814

Pamapimod

Also listed as Pamapimod (R-1503, Ro4402257)

Pamapimod (R-1503, Ro4402257) (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1·3 nM and 120 nM for p38α and p38β, respectively

ChemicalCAS449811-01-2MW406.38FormulaC19H20F2N4O4
CAS number
449811-01-2
Molecular weight
406.38
Formula
C19H20F2N4O4
Solubility
DMF： 30 mg/ml,DMSO： 30 mg/ml,DMSO：PBS(pH 7·2) (1：3)： 0·25 mg/ml,Ethanol： 0·33 mg/ml
InChIKey
JYYLVUFNAHSSFE-UHFFFAOYSA-N
Catalogue number
GC15814
Brand
GLPBIO
Computed properties PubChem CID 16220188 · XLogP 2.4 · TPSA 108 Ų · H-bond donors 3
XLogP
2.4
TPSA
108 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
29

SMILES CN1C2=NC(=NC=C2C=C(C1=O)OC3=C(C=C(C=C3)F)F)NC(CCO)CCO

Computed descriptors from PubChem (CID 16220188), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.