GC15778
ONX-0914 (PR-957)
Also known as (2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2S)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide
ONX-0914 (PR-957) is a specific inhibitor of the immunoproteasome subunits low molecular weight polypeptide 7 (LMP7) and low molecular weight polypeptide 2 (LMP2), with IC50 values of 0·34μM and 0·0057μM, respectively
ChemicalCAS960374-59-8MW580.67FormulaC31H40N4O7
- CAS number
- 960374-59-8
- Molecular weight
- 580.67
- Formula
- C31H40N4O7
- Solubility
- ≥ 29·0335mg/mL in DMSO, ≥ 69 mg/mL in EtOH
- InChIKey
- WQAVPPWWLLVGFK-FRDWYVIJSA-N
- Catalogue number
- GC15778
- Brand
- GLPBIO
Computed properties PubChem CID 46218908 · XLogP 1.9 · TPSA 139 Ų · H-bond donors 3
- XLogP
- 1.9
- TPSA
- 139 Ų
- H-bond donors
- 3
- H-bond acceptors
- 8
- Rotatable bonds
- 14
- Heavy atoms
- 42
SMILES C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)OC)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)[C@@]3(CO3)C)NC(=O)CN4CCOCC4
Computed descriptors from PubChem (CID 46218908), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il