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Chemical structure of Gedatolisib

GC15653

Gedatolisib

Also listed as PF-05212384 (PKI-587)

PF-05212384 (PKI-587) (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0·4 nM, 5·4 nM and 1·6 nM, respectively· PF-05212384 (PKI-587) is equally effective in both complexes of mTOR, mTORC1 and mTORC2

ChemicalCAS1197160-78-3MW615.73FormulaC32H41N9O4
CAS number
1197160-78-3
Molecular weight
615.73
Formula
C32H41N9O4
Solubility
≥ 15·4mg/mL in DMSO with gentle warming
InChIKey
DWZAEMINVBZMHQ-UHFFFAOYSA-N
Catalogue number
GC15653
Brand
GLPBIO
Computed properties PubChem CID 44516953 · XLogP 2.4 · TPSA 128 Ų · H-bond donors 2
XLogP
2.4
TPSA
128 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
45

SMILES CN(C)C1CCN(CC1)C(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCOCC6

Computed descriptors from PubChem (CID 44516953), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.