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Chemical structure of Methylprednisolone

GC15505

Methylprednisolone

Also known as (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

Methylprednisolone is a corticosteroid that interacts with the glucocorticoid receptor and inhibits cortisol secretion with an IC50 of 1·7ng/ml

ChemicalCAS83-43-2MW374.48FormulaC22H30O5
CAS number
83-43-2
Molecular weight
374.48
Formula
C22H30O5
Solubility
≥ 15·35 mg/mL in DMSO, ≥ 9·5 mg/mL in EtOH with ultrasonic
InChIKey
VHRSUDSXCMQTMA-PJHHCJLFSA-N
Catalogue number
GC15505
Brand
GLPBIO
Computed properties PubChem CID 6741 · XLogP 1.9 · TPSA 94.8 Ų · H-bond donors 3
XLogP
1.9
TPSA
94.8 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
2
Heavy atoms
27

SMILES C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(C[C@@H]([C@@H]2[C@@]4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O

Computed descriptors from PubChem (CID 6741), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.